However, based on current studies, antibodies to COVID-19 virus can be detected up to 4 months post-exposure. If you had symptoms consistent with COVID-19 within the past 3 weeks and tested negative, repeat testing in 1-2 weeks may yield a positive result. A non-reactive or negative test result means that the person does not have the virus. The result of COVID-19 antibody test cannot tell you whether or not you have a protective immunity against the virus. For example, for a disease prevalence of 1 %, the COVID-19 antibody test has a positive predictive value of 65 % and a negative predictive value of 99.9 %. Test strip marked 10B is a valid reactive test showing control line, antibody (Ab) and weak reactivity to antigen (Ag) lines. Whereas, for a disease prevalence of 10 %, the test has a positive predictive value of 95 % and a negative predictive value of 99.1 %. It is unclear at this time if a positive IgG infers immunity against future COVID-19 infection. Most people develop detectable antibodies approximately 30 days after infection, although some seroconvert later. Results of the test show whether you had a recent or prior COVID-19 infection. This means you have not been infected with COVID-19. Dr. Saptarshi Bandyopadhyay answered 20 … This test is most accurate when sample is collected 3-4 weeks after onset of symptoms or 3-4 weeks after exposure. The COVID-19 antibody test is not to be used for diagnosis of an active COVID-19 infection. Physicians are advised that billing the British Columbia Medical Services Plan (in BC) or the Ontario Health Insurance Plan (in ON) for ordering this service through LifeLabs is not authorized. A non-reactive HIV test indicates that there were no active HIV antibodies in the blood at the time of testing using a rapid HIV test, according to the Berkeley Free Clinic. due to lack of eligibility for testing). The customer accepts the risk of such events. Results of COVID-19 antibody tests may not always be accurate, especially if the test was done too soon after infection or the test quality is questionable. A negative, non-reactive, or not detected result means the test did not detect antibodies against COVID-19 at the time of testing. You achieve immunity by either previous infection and clearance of the virus or by immunization. Eligibility may vary, depending on the availability of tests. Health care providers and their patients should recognize that this risk is outside of LifeLabs’ control. Coronavirus Disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Positive antibody (serology) test results do not infer immunity and protection from re-infection, Serology results should not be used to exclude active infection, Antibody testing performed < 3 weeks after onset of symptoms has reduced clinical sensitivity and may lead to false negative results, Rare false positive results may be due to cross-reactivity with other coronaviruses, Immunosuppressed individuals or those with mild disease may not produce measurable antibody levels. The most commonly reported ones include fever, loss of smell, coughing, sore throat, shortness of breath or difficulty breathing, feeling weak or lethargic, chills, muscle pain, light-headedness or dizziness, headache, vomiting or diarrhea, slurred speech, and/or seizures. This means you have not been infected with COVID-19. An antibody test can only be administered by gathering blood, either through a finger prick or from a vein. The molecular test is used to diagnose infection. You must get this e-requisition signed by your healthcare provider, prior to visiting a LifeLabs PSC to get your blood sample collected. Type and severity of symptoms of an active COVID-19 infection vary greatly between individuals depending on the age, gender, and underlying medical conditions. A ‘Non-reactive’ (negative) result means that detectable levels of antibodies were not found in the sample. For most accurate results (results with highest sensitivity) it is recommended the antibody test is ordered 3-4 weeks post-onset of symptoms or post-exposure. Here are some critical facts about antibody testing: • Antibody testing indicates if your body has responded to the SARS CoV-2 COVID -19 virus • Testing Negative (Non-Reactive) does not mean you definitely don’t have an infection with the virus right now o Not everyone develops antibodies o It may be too soon for you to develop antibodies In Ontario, by writing ‘COVID-19 Antibodies’ in the ‘Other Tests’ section of the standard MOH-issued OHIP requisition. It does not mean they are currently infected. Reactive: You produced the COVID-19 IgG antibody and have a high likelihood of prior infection. This could mean that: A positive antibody test result means that antibodies were detected in your patient’s blood sample. Need help? Immunocompromised individuals may have low antibody responses to SARS-CoV-2. The molecular test (e.g. Non-Reactive: You tested negative for COVID-19 IgG antibody. These performance characteristics meet Health Canada requirements for COVID-19 antibody tests. Risks. Many different manufacturers rushed to put antibody tests on the market with little oversight. Description. Results will be available within 1-2 business days from sample collection. AZ (rapid test reactive) 8. This blood test detects prior infection, even if you never experienced symptoms. Some studies indicate that a small percentage of people infected with SARS-CoV-2 (<4%) do not have detectable antibodies. anti-HBs or HBsAb (Hepatitis B surface antibody) - A "positive" or "reactive" anti-HBs (or HBsAb) test result indicates that a person is protected against the hepatitis B virus. A positive antibody test result means that antibodies were detected in your blood sample. LifeLabs offers COVID-19 antibody testing as a patient-paid service for individuals who fall outside the coverage criteria set by public health. 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